Fluorinated amines
The fluorine atom is electronegative and reduces the basicity of adjacent amines, however, it is relatively small: only about 20% larger than hydrogen and significantly smaller that chlorine resulting in unique and useful properties. In many cases incorporation of fluorine results in improved DMPK properties. Below you will find examples of mono-fluoro, di-fluoro and trifluoromethyl substituted amines, many with a hydroxyl substituent or an ether linkage.
Search returned 702 hits.
Structure | Product info | Availability | Quantity / Price |
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Catalog ID
EN300-115962 Product class
Building Block
Name2,2-difluoroethan-1-amine ACD numberMFCD00798137 CAS number430-67-1 Formula MW81.1 CLogP-0.089 Storage conditionsRT Transport conditionsNormal See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 2x0.25 g, 2x0.5 g, 1x1 g, 1x2.5 g, 1x5 g, 1x10 gUSA Rush delivery(2 business days) available in New Jersey stock : 3x0.25 g, 2x0.5 g, 1x1 g, 1x2.5 g, 1x5 g | ||
Catalog ID
EN300-194473 Product class
Building Block
Name2-fluoroethan-1-amine hydrochloride ACD numberMFCD00008161 CAS number460-08-2 Formula MW99.5 CLogP-0.412 Storage conditionsRT Transport conditionsNormal See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g, 1x5 g, 1x10 gUSA Rush delivery(2 business days) available in New Jersey stock : 4x0.25 g, 4x0.5 g, 2x1 g, 1x2.5 g, 1x5 g, 1x10 g | ||
Catalog ID
EN300-204507 Product class
Building Block
Name(3-fluoroazetidin-3-yl)methanol ACD numberMFCD18633069 CAS number1268520-93-9 Formula MW105.1 CLogP-0.908 Storage conditions+4 Transport conditionsNormal See details | Now available as 91.0% pureGlobal stock:0.2 g | ||
Catalog ID
EN300-6970573 Product class
Building Block
Name3-(fluoromethyl)oxetan-3-amine ACD numberMFCD31727894 CAS number1782527-32-5 Formula MW105.1 CLogP-0.095 Storage conditions-10 Transport conditionsIce pack See details | Purity: 95.0%Global stock:> 10 g USA Rush delivery(2 business days) available in New Jersey stock : 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g, 1x5 g | ||
Catalog ID
EN300-175608 Product class
Building Block
Name2-amino-4-fluorobutan-1-ol ACD numberMFCD19216262 CAS number1314976-96-9 Formula MW107.1 CLogP-1.034 Storage conditions+4 Transport conditionsIce pack See details | Purity: 95.0%Global stock:6.7 g USA Rush delivery(2 business days) available in New Jersey stock : 1x0.05 g, 1x0.1 g, 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g | ||
Catalog ID
EN300-100454 Product class
Building Block
Name3-amino-1,1-difluoropropan-2-ol ACD numberMFCD16805790 CAS number433-46-5 Formula MW111.1 CLogP-0.94 Storage conditions-10 Transport conditionsIce pack See details | Purity: 95.0%Global stock:7.6 g EU Rush delivery : (2 business days) 4x0.05 g, 4x0.1 g, 4x0.25 g, 4x0.5 g, 4x1 gUSA Rush delivery(2 business days) available in New Jersey stock : 1x0.05 g | ||
Catalog ID
EN300-190781 Product class
Building Block
Name2-(difluoromethoxy)ethan-1-amine ACD numberMFCD28397342 CAS number1599344-15-6 Formula MW111.1 CLogP-0.226 Storage conditions-10 Transport conditionsIce pack See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 1x0.05 g, 1x0.1 g, 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g, 1x5 gUSA Rush delivery(2 business days) available in New Jersey stock : 6x0.05 g, 5x0.1 g, 5x0.25 g, 5x0.5 g, 5x1 g | ||
Catalog ID
EN300-139846 Product class
Building Block
Name3-amino-2,2-difluoropropan-1-ol ACD numberMFCD19207959 CAS number155310-11-5 Formula MW111.1 CLogP-0.011 Storage conditions+4 Transport conditionsNormal See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 2x0.05 g, 2x0.1 g, 2x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g, 1x5 gUSA Rush delivery(2 business days) available in New Jersey stock : 2x0.05 g, 2x0.1 g, 2x0.25 g, 2x0.5 g, 1x1 g, 1x2.5 g, 1x5 g | ||
Catalog ID
EN300-7461074 Product class
Building Block
Name2-fluoroprop-2-en-1-amine hydrochloride ACD numberMFCD17014871 CAS number322637-47-8 Formula MW111.5 CLogP0.213 Storage conditionsRT Transport conditionsNormal See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 2x0.05 g, 2x0.1 g, 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g, 1x5 g, 1x10 gUSA Rush delivery(2 business days) available in New Jersey stock : 3x0.05 g, 3x0.1 g, 2x0.25 g, 2x0.5 g, 1x1 g, 1x2.5 g, 1x5 g | ||
Catalog ID
EN300-89604 Product class
Building Block
Name1,1,1-trifluoropropan-2-amine ACD numberMFCD04973020 CAS number421-49-8 Formula MW113.1 CLogP0.438 Storage conditions+4 Transport conditionsIce pack See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 gUSA Rush delivery(2 business days) available in New Jersey stock : 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g, 1x5 g | ||
Catalog ID
EN300-344955 Product class
Building Block
Name5-fluoropyrimidin-2-amine ACD numberMFCD11846500 CAS number1683-85-8 Formula MW113.1 CLogP-0.135 Storage conditionsRT Transport conditionsNormal See details | Purity: 95.0%Global stock:> 10 g USA Rush delivery(2 business days) available in New Jersey stock : 3x0.25 g, 3x0.5 g, 3x1 g, 1x2.5 g, 1x5 g, 1x10 g | ||
Catalog ID
EN300-7461639 Product class
Building Block
Name3-fluoropropan-1-amine hydrochloride ACD numberMFCD07369956 CAS number64068-31-1 Formula MW113.6 CLogP-0.183 Storage conditions+4 Transport conditionsIce pack See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 2x0.25 g, 2x0.5 g, 2x1 g, 2x2.5 g, 1x5 g, 1x10 gUSA Rush delivery(2 business days) available in New Jersey stock : 2x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g | ||
Catalog ID
EN300-214040 Product class
Building Block
Name1-fluoropropan-2-amine hydrochloride ACD numberMFCD20489620 CAS number921602-78-0 Formula MW113.6 CLogP-0.103 Storage conditionsRT Transport conditionsNormal See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 2x0.05 g, 2x0.1 g, 2x0.25 g, 2x0.5 g, 1x1 g, 1x2.5 g, 1x5 gUSA Rush delivery(2 business days) available in New Jersey stock : 2x0.05 g, 2x0.1 g, 2x0.25 g, 2x0.5 g, 2x1 g, 2x2.5 g, 1x5 g | ||
Catalog ID
EN300-1081128 Product class
Building Block
NameO-(2-fluoroethyl)hydroxylamine hydrochloride ACD numberMFCD13196691 CAS number95068-26-1 Formula MW115.5 CLogP-0.801 Storage conditions+4 Transport conditionsNormal See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 1x0.05 g, 1x0.1 g, 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g, 1x5 gUSA Rush delivery(2 business days) available in New Jersey stock : 3x0.05 g, 3x0.1 g, 3x0.25 g, 2x0.5 g, 2x1 g, 1x2.5 g | ||
Catalog ID
EN300-200827 Product class
Building Block
Name2-(1-fluorocyclobutyl)ethan-1-amine ACD numberMFCD28246495 CAS number1803593-31-8 Formula MW117.2 CLogP0.94 Storage conditions-10 Transport conditionsIce pack See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 5x0.05 g, 5x0.1 g, 5x0.25 g, 5x0.5 g, 4x1 gUSA Rush delivery(2 business days) available in New Jersey stock : 6x0.05 g, 6x0.1 g, 6x0.25 g, 5x0.5 g, 3x1 g | ||
Catalog ID
EN300-96615 Product class
Building Block
Name2,2-difluoroethan-1-amine hydrochloride ACD numberMFCD04038283 CAS number79667-91-7 Formula MW117.5 CLogP-0.089 Storage conditionsRT Transport conditionsNormal See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 1x0.25 g, 1x0.5 g, 1x1 gUSA Rush delivery(2 business days) available in New Jersey stock : 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g | ||
Catalog ID
EN300-6430616 Product class
Building Block
Name3-(difluoromethyl)oxetan-3-amine ACD numberMFCD32663199 CAS number1779926-68-9 Formula MW123.1 CLogP-0.072 Storage conditions-10 Transport conditionsIce pack See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 3x0.05 g, 3x0.1 g, 3x0.25 g, 3x0.5 g, 3x1 gUSA Rush delivery(2 business days) available in New Jersey stock : 3x0.05 g, 3x0.1 g, 3x0.25 g, 3x0.5 g, 2x1 g | ||
Catalog ID
EN300-156762 Product class
Building Block
Name3-(difluoromethoxy)azetidine ACD numberMFCD28132440 CAS number1403993-56-5 Formula MW123.1 CLogP0.403 Storage conditions-70 Transport conditionsDry ice See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 5x0.25 g, 5x0.5 g, 4x1 gUSA Rush delivery(2 business days) available in New Jersey stock : 5x0.25 g, 5x0.5 g, 4x1 g | ||
Catalog ID
EN300-90869 Product class
Building Block
Name2-(trifluoromethyl)azetidine ACD numberMFCD11042768 CAS number1040331-55-2 Formula MW125.1 CLogP0.51 Storage conditions-10 Transport conditionsIce pack See details | Purity: 95.0%Global stock:> 10 g EU Rush delivery : (2 business days) 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 g, 1x5 gUSA Rush delivery(2 business days) available in New Jersey stock : 3x0.25 g, 1x0.5 g, 1x1 g | ||
Catalog ID
EN300-223035 Product class
Building Block
Name3-amino-4,4-difluorobutan-1-ol ACD numberMFCD29033879 CAS number1785430-93-4 Formula MW125.1 CLogP-0.602 Storage conditions+4 Transport conditionsNormal See details | Purity: 95.0%Global stock:8.6 g EU Rush delivery : (2 business days) 1x0.05 g, 1x0.1 g, 1x0.25 g, 1x0.5 g, 1x1 g, 1x2.5 gUSA Rush delivery(2 business days) available in New Jersey stock : 3x0.05 g, 3x0.1 g, 3x0.25 g, 1x0.5 g |