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Sumatriptan succinate

Sumax, Imitrex, Sumatran, Imigran, Sumatriptanum, GR 43175 A, GR 43175 C, GR 43175 X, SN 308

Technical Data

Chemical name:Sumatriptan succinate
Formula:C18H27N3O6S
Molecular weight:413.5
CAS number:103628-48-4
SMILES:OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

Cat. No. BRC0060

BRC0060

Prices

1.0 mg $ 83.0
2.0 mg $ 86.0
5.0 mg $ 91.0
10.0 mg $ 118.0
20.0 mg $ 170.0
25.0 mg $ 190.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Vasoconstrictors   

Target:

G-Protein-Coupled Receptors (GPCRs)    5-hydroxytryptamine receptor (5-HT receptor) inhibitors    Ion Channels    Aquaporins    Ligand-gated ion channels    Transporters    Aquaporins   

Description:

Sumatriptan, an antimigraine drug, is a selective agonist of vascular serotonin ((5-hydroxytryptamine; 5-HT) type 1-like receptors, likely the 5-HT1D and 5-HT1B subtypes).

Targets:5-hydroxytryptamine receptor 1D, 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1F, 5-hydroxytryptamine receptor 1A
References:
1. Pain. 2008 Oct 31; 139(3):533-40.; 
2. Eur.J.Pharmacol. 2004; 497, 181.; 
3. Headache. 1990; 30, 554.;