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Acetazolamide

Defiltran, Diacarb, Diamox, Diluran, Glaupax

Technical Data

Chemical name:Acetazolamide
Formula:C4H6N4O3S2
Molecular weight:222.2
CAS number:59-66-5
SMILES:CC(=O)Nc1nnc(s1)S(N)(=O)=O

Cat. No. BRC0192

BRC0192

Prices

1.0 mg $ 55.0
2.0 mg $ 56.0
5.0 mg $ 59.0
10.0 mg $ 78.0
20.0 mg $ 93.0
25.0 mg $ 100.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anticonvulsants    Cardiovascular    Diuretics   

Target:

Enzymes    Carbonic Anhydrase    Ion Channels    Aquaporins    Transporters    Aquaporins   

Description:

Acetazolamide is a potent carbonic anhydrase inhibitor, effective in the control of fluid secretion, in the treatment of certain convulsive disorders and in the promotion of diuresis in instances of abnormal fluid retention.

Targets:Carbonic anhydrase 1, Carbonic anhydrase 14, Carbonic anhydrase 2, Carbonic anhydrase 3, Carbonic anhydrase 4, Carbonic anhydrase 7, Aquaporin-1
References:
1. Crit. Care. 2012; 16(4), 318.; 
2. J. Appl. Physiol. 2007; 102(4), 1313-1322.; 
3. Br. J. Pharmacol. 2010; 161(1), 1-16.;