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Lamotrigine

Lamictal, BW-430C

Technical Data

Chemical name:Lamotrigine
Formula:C9H7Cl2N5
Molecular weight:256.1
CAS number:84057-84-1
SMILES:Nc1nnc(c(N)n1)-c1cccc(Cl)c1Cl

Cat. No. BRC0155

BRC0155

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anticonvulsants    CNS Agents    Antidepressive Agents   

Target:

G-Protein-Coupled Receptors (GPCRs)    5-hydroxytryptamine receptor (5-HT receptor) inhibitors    Ion Channels    Aquaporins    Sodium channel    Ligand-gated ion channels    Transporters    Aquaporins   

Description:

Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. For epilepsy it is used to treat partial seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Lamotrigine also acts as a mood stabilizer.

Targets:Sodium channel protein type 2 subunit alpha, 5-HT (human platelets), 5-HT (rat brain synaptosomes)
References:
1. Curr Pain Headache Rep. 2004 Jun; 8(3):212-6.; 
2. J Clin Psychiatry. 2003 Apr; 64(4):403-7.; 
3. Eur J Pain. 2002; 6 Suppl A:61-8.; 
4. Clin Ther. 2003 Oct; 25(10):2506-38.; 
5. Pak J Biol Sci. 2009 Jan 1; 12(1):33-9.;