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Repaglinide

AG-EE 623ZW, AGEE 623, Eurepa

Technical Data

Chemical name:Repaglinide
Formula:C27H36N2O4
Molecular weight:452.6
CAS number:135062-02-1
SMILES:CCOc1cc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N2CCCCC2)ccc1C(O)=O

Cat. No. BRC0762

BRC0762

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Antidiabetic   

Target:

Nuclear Receptors (nuclear hormone receptors)    Peroxisome proliferator-activated receptor (PPAR)   

Description:

Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus. It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release.

Targets:ATP-binding cassette sub-family C member 8, Peroxisome proliferator-activated receptor gamma
References:
1. Br J Pharmacol. 2005; 144, 4, 551.; 
2. J. Pharmacol. Exp. Ther. 2000; 293, 2, 444.; 
3. Bioorg. Med. Chem. Lett. 2004; 14, 20, 5205.;