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Phenytoin

NSC-8722;

Technical Data

Chemical name:Phenytoin
Formula:C15H12N2O2
Molecular weight:252.3
CAS number:57-41-0
SMILES:O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1

Cat. No. BRC0974

BRC0974

Prices

1.0 mg $ 55.0
2.0 mg $ 56.0
5.0 mg $ 59.0
10.0 mg $ 78.0
20.0 mg $ 93.0
25.0 mg $ 100.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anticonvulsants    Cardiovascular    CNS Agents   

Target:

Ion Channels    Aquaporins    Sodium channel    Transporters    Aquaporins   

Description:

Phenytoin is an antiepileptic drug. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation.

Targets:Sodium channel protein type 5 subunit alpha; Sodium channel protein type 1 subunit alpha; Nuclear receptor subfamily 1 group I member 2; Sodium channel subunit beta-1; Sodium channel protein type 3 subunit alpha;
References:
1. Curr Drug Metab. 2007; 8, 4, 315 - 323.; 2. Mol Pharmacol. 2014; 85, 1, 162 - 174.; 3. J Med Chem. 2004; 47, 4, 907 - 914.;