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Curcumin

E100; INS-100(I); NSC-32982;

Technical Data

Chemical name:Curcumin
Formula:C21H20O6
Molecular weight:368.4
CAS number:94875-80-6
SMILES:COC1=C(O)C=CC(C=CC(=O)CC(=O)C=CC2=CC(OC)=C(O)C=C2)=C1

Cat. No. BRC1060

BRC1060

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Analgesics    Anti-cancer agents    Anti-Inflammatory    CNS Agents   

Target:

G-Protein-Coupled Receptors (GPCRs)    GABA receptors    Enzymes    Reductases    Nuclear Receptors (nuclear hormone receptors)    Peroxisome proliferator-activated receptor (PPAR)   

Description:

Curcumin is a yellow-orange dye and possesses a vast number of biological targets. It is an antitumor, anti-inflammatory, and antioxidant agent.

Targets:Peroxisome proliferator-activated receptor gamma; Vitamin D3 receptor; Multidrug resistance-associated protein 5; Carbonyl reductase [NADPH] 1; Glutathione S-transferase P;
References:
1. Eur J Med Chem. 2016; 114, 365 - 379.; 2. Chem Biol Drug Des. 2014; 83, 6, 670 - 681.; 3. Journal of Biol Chem. 2014; 289, 45, 31397 - 31410.;