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GQ-16

Technical Data

Chemical name:GQ-16
Formula:C19H16BrNO3S
Molecular weight:418.3
CAS number:777075-57-7
SMILES:COc1ccc(Br)cc1C=C1SC(=O)N(Cc2ccc(C)cc2)C1=O

Cat. No. BRC0881

BRC0881

Prices

1.0 mg $ 83.0
2.0 mg $ 86.0
5.0 mg $ 91.0
10.0 mg $ 119.0
20.0 mg $ 205.0
25.0 mg $ 225.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Antidiabetic   

Target:

Nuclear Receptors (nuclear hormone receptors)    Peroxisome proliferator-activated receptor (PPAR)   

Description:

GQ-16 is a novel effective inhibitor of Cdk5-mediated phosphorylation of PPARγ, promotes insulin sensitization without weight gain.

Targets:PPARγ,
References:
1. J. Biol. Chem. 2012; 287(33), 28169-28179.; 
2. Eur. J. Med. Chem. 2016; 124, 49-62.; 
3. Cardiovascular Pathology. 2013; 22(1), 81-90.;