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Glipizide

Aldiab, CP 28720, Digrin, K 4024, Melizide

Technical Data

Chemical name:Glipizide
Formula:C21H27N5O4S
Molecular weight:445.5
CAS number:29094-61-9
SMILES:Cc1cnc(cn1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1

Cat. No. BRC0735

BRC0735

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Antidiabetic   

Target:

Nuclear Receptors (nuclear hormone receptors)    Peroxisome proliferator-activated receptor (PPAR)   

Description:

Glipizide is an oral hypoglycemic agent which is rapidly absorbed and completely metabolized. It is a second-generation sulfonylurea, is used with diet to lower blood glucose in patients with diabetes mellitus type II.

Targets:ATP-binding cassette sub-family C member 8, Peroxisome proliferator-activated receptor gamma
References:
1. J. Pharmacol. Exp. Ther. 1995; 273, 2, 778.; 
2. Eur. J. Med. Chem. 2004; 39, 10, 835.; 
3. Br J Pharmacol. 2000; 129, 7, 1323.;