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Fenofibrate

NSC 281319, LF 178, FNF

Technical Data

Chemical name:Fenofibrate
Formula:C20H21ClO4
Molecular weight:360.8
CAS number:49562-28-9
SMILES:CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1

Cat. No. BRC0862

BRC0862

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Target:

Nuclear Receptors (nuclear hormone receptors)    Peroxisome proliferator-activated receptor (PPAR)   

Description:

Fenofibrate is PPARα agonist, lipid regulating drug. It increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expression.

Targets:Peroxisome proliferator-activated receptor alpha, Metalloproteinase, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor delta, Nuclear receptor subfamily 1 group I member 2
References:
1. J. Med. Chem. 2009; 52, 17, 5344 - 5355.; 
2. Biochem. Pharmacol. 2005; 70, 11, 1653 - 1663.; 
3. J. Med. Chem. 2008; 51, 13, 3755 - 3764.;