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Nateglinide

Starlix, Starsis, Fastic, Senaglinide, A-4166

Technical Data

Chemical name:Nateglinide
Formula:C19H27NO3
Molecular weight:317.4
CAS number:105816-04-4
SMILES:CC(C)[C@H]1CC[C@@H](CC1)C(=O)N[C@H](Cc1ccccc1)C(O)=O

Cat. No. BRC0163

BRC0163

Prices

1.0 mg $ 83.0
2.0 mg $ 85.0
5.0 mg $ 90.0
10.0 mg $ 117.0
20.0 mg $ 160.0
25.0 mg $ 180.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Antidiabetic   

Target:

Nuclear Receptors (nuclear hormone receptors)    Peroxisome proliferator-activated receptor (PPAR)    Ion Channels    Potassium channel   

Description:

Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release.

Targets:ATP-binding cassette sub-family C member 8, Peroxisome proliferator-activated receptor gamma
References:
1. J.Pharmacol.Exp.Ther. 2003; 304, 1025.; 
2. J.Pharmacol.Exp.Ther. 1999; 291, 1372.;